•The average Ebola case fatality rate is around 50%. "In conclusion, we have identified Rhodiola rosea as a potent Ebola virus entry agent", the researchers summarize their findings. They are the best at what they do and will never turn you down. Ebola virus then spreads from person to person through direct contact with blood or body fluids of a person who is sick with or has died from Ebola virus disease. Over the past few weeks, WATHI has delved into one of the most devastating health emergencies in West Africa: the Ebola virus. 1997. ABSTRACT: Ebola virus disease, caused by the filovirus Ebolavirus, leads to viral hemorrhagic fever and is fatal in many cases. Jahrling, P.B. The virus is considered to be extremely dangerous. Conclusion Ebola, a major threat to today's society, is threatening all parts of today's culture. Ebola is a viral disease that may present in different ways in humans. Ebola virus likely causes little or no damage to bats because of a long-term interaction between the host (bats) and the virus. There are five known strains of the virus. Then your organs become liquefied. The periodic outbreaks of the disease offer examples of how selective pressures imposed on a pathogen follow the predictions of the Trade-off hypothesis linking virulence (and attendant host mortality) with rate of transmission. The Lancet 1990;335:502-05. 2020 Jan 7. doi: 10.1111/tmi.13369. There are five known strains of the virus. Outbreaks of Ebola in sub-Saharan Africa have resulted in fatality rates of up to 90%. Conclusion Ebola, a major threat to today's society, is threatening all parts of today's culture. Good Essays. Infectious Ebola virions are usually 920 nm in length, 80 nm in diameter, and have a membrane stolen from the host cell by budding. Conclusion. Alternate Text: The figure above is a line graph showing the cumulative number of cases of Ebola virus disease reported from Guinea, Liberia, Sierra Leone, Nigeria, and Senegal during March 29-September 20, 2014. This usually results in death(www.encyclopedia.com). After Ebola virus disease (EVD) emerged in Sierra Leone in 2014, a total of 8,704 confirmed cases and 3,955 deaths had been reported as of the declaration of EVD transmission-free status on November 7, 2015 ().Approximately 4,000 survivors are in the country, and evidence of the frequency and duration of sequelae over an extended period is limited in this cohort. After … Ebola virus disease distribution map: cases of Ebola virus disease in Africa since. Overall case fatality has been 25% for Bundibugyo virus disease, 50% for Sudan virus disease, and 80% for Ebola virus disease. Ebola virus disease distribution map: cases of Ebola virus disease in Africa since. Page 1 of 50 - About 500 essays. This usually results in death(www.encyclopedia.com). Virus Hunter: Thirty Years of Battling Hot Viruses Around the World. Ebola Virus Conclusion Essay of TFTH Ebola Virus Conclusion Essay only. The Ebola Virus and Ebola Hemorrhagic Fever present an interesting case for evolution of virulence in a pathogen. Conclusion. Emerging viral diseases have become major public health problem in the World. Ebola is a deadly infectious disease with an average case fatality rate of 50%. One affects only nonhuman primates (monkeys, gorillas, and chimpanzees) and pigs. IIX. The epidemiology and pathogenesis of Ebola virus disease will be presented here. CONCLUSION: Our results provide novel molecular detail on the interaction of Reston virus VP24 and Ebola virus VP24 with human KPNA5. Ebola Virus Essay Conclusion some of them sound similar to: Please help me write my essay! One affects only nonhuman primates (monkeys, gorillas, and chimpanzees) and pigs. Conclusion: Ebola virus is highly virulent and fatal, and treatment options are limited. Inventive methods are directed to detection and treatment of EboBun infection. It occurs when clients beg us for college essay help, claiming us to be their final chance. infecting fruit bats, the Ebola virus found a mutation allowing it to spread to humans. The following report contains info on the characteristics and history of the Ebola Virus. Ebola Virus Conclusion Essay, components of literature review pdf, que significa research paper en ingles, rose homework hotline. Ebola virus has been a threat to human health due to dangerous, highly lethal and infectious behavior since its discovery in 1976. [[{"attributes":{},"fields":{}}]] Hypsignathus … This time last month, national authorities in the African nation of … Ebola virus then spreads from person to person through direct contact with blood or body fluids of a person who is sick with or has died from Ebola virus disease. et al. Objective: Ebola virus disease (EVD) is a life-threatening viral disease. Global cooperation, collaboration and investment are necessary to ensure a safer future. Ebola Virus Disease Information for Clinicians in U.S. Healthcare Settings; Clinician Outreach and Communication Activity (COCA) Call- What U.S. Ebola viruses cause a severe and often deadly illness known as Ebola virus disease (EVD; previously referred to as Ebola hemorrhagic fever). That conclusion comes from a sweeping analysis of 99 Ebola virus genome sequences that comprise some 70 percent of the Ebola patients diagnosed in Sierra Leone in late May to mid-June. Informal, Ebola virus epidemic in West Africa → Ebola virus outbreak 2014, No conclusion, 7 October 2014, Talk:Western African Ebola virus epidemic/Archive 6#Page name; Informal, Ebola virus epidemic in West Africa → 2014 Ebola Crisis, Closed and directed to RM, 9 October 2014, Talk:Western African Ebola virus epidemic/Archive 6#Title Change Ebola disease •Ebola disease is a severe, often fatal illness in humans. You may not even expect your assignments to be so good but when you read your essay done by TFTH, you will instantly realise how good they are!’ Conclusion: Ebola virus is highly virulent and fatal, and treatment options are limited. Along with the Marburg virus it is a member of the family Filoviridae. For this purpose, a gold SPR chip was modified with 4-mercaptobenzoic acid (4-MBA), and modification was confirmed by … Essay: The Ebola Virus. Due to the fact that researchers still do not completely understand the pathophysiology of the virus this disease is hard to control and no cure is known yet. The outbreaks involved more than 500 cases and at least 400 deaths caused by clinical hemorrhagic fever. Massive destruction of the liver is a hallmark feature of Ebola virus infection. 1. - Because they are stressed out. It is caused by six viral species that belongs to genus Ebolavirus. Combined Simian Hemorrhagic Fever and Ebola Virus Infection in Cynomolgus Monkeys. Ebola GP was found to have accumulated in the endoplasmic reticulum . Ebola virus definition is - any of several filoviruses (genus Ebolavirus and especially species Zaire ebolavirus) of African origin that cause an often fatal hemorrhagic fever. Introduction. Executive Summary The latest epidemic of Ebola Virus Disease (EVD) in the Democratic Republic of Congo (DRC) has rapidly evolved into the second largest outbreak in history. Victims can die of … Death rate ranges between 30% and 90%, the first EVD outbreak was reported in the 1970s in Zaire. Ebola virus disease: background and summary. 3 April 2014 - WHO is supporting the national authorities in the response to an outbreak of Ebola virus disease (EVD; formerly known as Ebola haemorrhagic fever). The outbreak is now confirmed to be caused by a strain of ebolavirus with very close homology (98%) to the Zaire ebolavirus. The Deadly Ebola Virus The Ebola Virus is the common name for several strains of virus, three of which are known to cause hemorrhagic fever in humans, which is characterized by massive bleeding and destruction of internal tissues. Several experimental and existing therapies may be options for preventing and treating Ebola virus disease. Ebola virus disease (EVD) is a rare but serious disease caused by infection of the Ebola virus. Ebola Virus disease (EVD) mostly affects people and nonhuman primates like monkeys, gorillas and chimpanzees. It is caused by an infection with a group of viruses within the genus Ebola virus. Let us tell you that Ebola Virus disease is also known as Ebola haemorrhagic fever. No doubt it often causes fatal illness in humans. When he returns he warns his boss, Brigadier-Gen. Ford, of the lethal nature of the virus and wants to put out an alert. "This traditional Chinese medicine has potent anti-Ebola activity and proven safety profile, making it a promising antiviral for further development." The Ebola virus has a tropism for liver cells and macrophages, macrophages are cells that engulf bacteria and help the body defend against disease. Many of the hospitals and staff members were unaware of the symptoms and transmission of this virulent virus until it was too late and it spread among patients and staff members. Once the zoonotic transmission takes place, the virus is extremely contagious. Compositions are provided that are operable as immunogens to elicit and immune response or protection from EboBun challenge in a subject such as a primate. Conclusion Conclusions & recommendations. Latest reports from WHO suggest that the Ebola virus disease outbreak in North Kivu and Ituri provinces, DR Congo, is serious and rapidly escalating. Do you know why almost all your classmates seek writing help? The first an outbreak timeline, the next three are a basic overview of the deadly virus. After being infected with the Ebola virus it takes 2-21 days to take effect. in March. The Filoviridae family is negative-sense, or negative-strand, RNA viruses. The symptoms last for 2 to 21 days. Early symptoms of EVD include high fever (temperature of up to 40°C), malaise, fatigue, and body aches (see … Preliminary report: isolation of Ebola virus from monkeys imported to USA. Four of them affect people. The first an outbreak timeline, the next three are a basic overview of the deadly virus. Sometimes we can even detect notes of either desperation Ebola Virus Essay Conclusion or anxiety. Ebola haemorrhagic fever (Ebola HF), one of the several VHFs, is The current (2014) West Africa Ebola virus outbreak was significant recognized worldwide as a severe, often deadly disease in humans as it was the largest and the most complex Ebola outbreak till and non-human primates (monkeys, chimpanzees and gorillas). In this paper one will be presented with six major points of analyses. The main viral determinant of Ebola virus pathogenicity, inducing cytotoxic effects in human endothelial cells, is still uncertain but usually associated with the intracellular synthesis or transport of the gene product of the Ebola virus surface virion GP to the cell surface. Ebola can be spread through direct contact (through broken skin or mucous membranes) with infected blood or body fluids or objects that have been contaminated with infected body fluids. However, Ebola virus is often deadly to other species, including humans, chimpanzees, and gorillas. Common clinical manifestations of EVD include hemorrhagic fever, headache, severe fatigue, muscle aches, and gastrointestinal symptoms such as diarrhea and vomiting (“Ebola Virus,” n.d.). “Taken together, our results clearly point to the conclusion that [Ebola virus] has gradually spread across central Africa from an origin near Yambuku in the mid-1970s,” they wrote. The virus is transmitted from wildlife to people through contact with infected fruit bats, or through intermediate hosts Ebola Virus Essay Conclusion of MA and PhD qualified experts working tirelessly to provide high quality customized writing solutions to all your assignments including Ebola Virus Essay Conclusion essays, term papers, research papers, dissertations, coursework and projects. Research on Ebola Abstract In the United States of America there was an outbreak in 2014. Ebola Virus. Ebola virus kills as many as 90% of the people it infects. In this paper one will be presented with six major points of analyses. Initial stages of Ebola virus infection are nonspecific, which makes the differential diagnosis broad; therefore, clinical suspicion of the infection with prompt isolation is very important in the context of a history of exposure. Here, different monoclonal antibodies (mAb1, mAb2 and mAb3) of Ebola virus were screened in a real-time and label-free manner using surface plasmon resonance (SPR) to select an appropriate antibody for biosensor applications against a biological warfare agent. This virus is an acute and often fatal illness. Peters, C.J. When he returns he warns his boss, Brigadier-Gen. Ford, of the lethal nature of the virus and wants to put out an alert. Ebola virus was discovered in 1976 when two severe epidemics of hemorrhagic fever occurred in Sudan and Zaire. Several experimental and existing therapies may be options for preventing and treating Ebola virus disease. In the case of Ebola, there was a failure to respond, both by the global and local communities, to recognized risks of an outbreak that were clearly identified by the global community during previous epidemics.16The The virus also can remain in breast milk, amniotic fluid, eye fluid, and spinal column fluid. Ebola survivors may have lasting side effects from the virus. These could include fatigue, muscle aches, stomach pain, and eye problems. How do I know if my symptoms are related to Ebola virus disease? Lack of a consistent Ebola case definition was an early impediment in the response. Ebola virus human infection initially presents with nonspecific symptoms such as fever, vomiting, and severe diarrhea. Ebola Virus Disease (EVD), formally known as Ebola Hemorrhagic Fever, which is a severe, often fatal illness in humans. Subsequent outbreaks of Ebola hemorrhagic fever have occurred in Uganda Congo, Gabon, Sudan, Ivory Coast. Ebola virus is normally considered as a conceivable biological weapon, thus there is a crucial need to develop effective antiviral drugs and vaccines. Filoviruses (Ebola) are helical, non-segmented, negative, single-stranded RNA viruses, polymorphic, noninfectious, and have variable lengths. Ebola is a rare but deadly virus that causes fever, body ache, diarrhoea etc. Compositions and methods including and related to the Ebola Bundibugyo virus (EboBun) are provided. Introduction Ebola hemorrhagic fever or Ebola HF is a dreadful and fatal disease in both humans and nonhuman primates, and is caused by an infection of the Ebola virus. natural hosts of Ebola virus. Sources: Situation reports received from the ministries of health of Guinea, Liberia, Nigeria, Senegal, and Sierra Leone, and the World Health Organization. It causes loads of Internal bleeding and vomitting. Each of the known cases and outbreaks of Ebola Virus Disease are described below by year or country. The clinical manifestations, diagnosis, treatment, and prevention of Ebola virus disease are discussed elsewhere. The Ebola virus poses significant threat to humans and animals. Conclusion. Pharmacists can play a large role in the management of the Ebola virus by educating and reassuring the public, particularly those traveling to endemic areas ( … The Ebola virus basically causes uncontrollable bleeding externally and internally. This virus does in ten days what it takes AIDS ten years to do. [Epub ahead of print] Association between treatment with oral third-generation cephalosporin antibiotics and mortality outcomes in Ebola virus disease: a multinational retrospective cohort study. Conclusion. 10. Then Bundibugyo in yellow on that map. This paper serves as an overview of the virus, including symptoms, diagnosis, and treatments. Ebola Virus: A notoriously deadly virus that causes severe symptoms, the most prominent being high fever and massive internal bleeding. New Ebola Outbreak Suggests The Virus Might Lurk For Years Inside People. Ebola Virus Disease is a rare but deadly disease caused by a virus transmitted initially from animals to humans. Initial stages of Ebola virus infection are nonspecific, which makes the differential diagnosis broad; therefore, clinical suspicion of the infection with prompt isolation is very important in the context of a history of exposure. Thus, the objective of this review is to discuss the re-emergence of Ebola. The results indicate a weaker interaction of Reston virus VP24 with KPNA5 than Ebola virus VP24, which is probably associated with a decreased ability to interfere with the host cell interferon response. The Ebola virus is found in animal reservoirs and can be transmitted to humans in the case of “inadvertent contact”. Ebola virus disease (EVD) in West Africa was first reported during early March 2014 in Guinea’s 3 southeastern prefectures (Gueckedou, Macenta, and Kissidougou), which border Liberia and Sierra Leone; however, retrospective investigations indicate Ebola virus (EBOV) transmission might have occurred in Guinea since December 2013 (1–4).On March 27, 2014, EVD was reported in … 40 Years of Ebola Virus Disease around the World. In conclusion, World Health Organization said that the Ebola outbreak that occurred in March 2014 was the most important to happen yet in history by claiming more than 11,300 people's lives and infecting over 28,500 people all over the world (World Health Organization, 2016, par. After Ebola virus disease (EVD) emerged in Sierra Leone in 2014, a total of 8,704 confirmed cases and 3,955 deaths had been reported as of the declaration of EVD transmission-free status on November 7, 2015 ().Approximately 4,000 survivors are in the country, and evidence of the frequency and duration of sequelae over an extended period is limited in this cohort. It has hurt many people and cost them lots of money. 570 Words; 3 Pages; 3 Works Cited; The Ebola Virus. Trop Med Int Health. The Ebola Virus. The virus is considered to be extremely dangerous. Our tutors belong to some prestigious institutions of the world which include: Your personal information will not be disclosed to any third parties; Early supportive care with rehydration, symptomatic treatment improves survival. A virus is an ultramicroscopic infectious organism that, having no independent metabolic activity, can replicate only within a cell of another host organism. That is the initial conclusion of a harsh new report released by a group known as the Ebola Interim Assessment Panel, which was commissioned by the W.H.O. Ebola virus was first described in 1976 near the Ebola River in what is now the Democratic Republic of Congo. Recent years have seen dramatic increases in the size and frequency of Ebola outbreaks. Fatality rates during … Vomiting, diarrhea, rashes, limited kidney and liver functions, and internal and external bleeding follow this. A virus similar to Ebola & Lassa is discovered in Africa in 1969. References. When it enters the body, it kills cells and also makes some of them to … The following report contains info on the characteristics and history of the Ebola Virus. _____ Warning!!! The bubonic plague’s lack of ability to mutate quickly only adds to the conclusion that the Ebola virus would result in far more devastation then an outbreak of the Black Plague. A virus consists of a core of nucleic acid, either RNA or DNA, surrounded by a coating of antigenic protein and sometimes a lipid layer surrounds it as well. Since the conclusion of the West African epidemic, the Zaire species has been responsible for several additional outbreaks in the DRC and one in Guinea. And the other Ebola virus like Sudan in blue in the map are called Sudan virus and not Ebola in the name of the species. Ebola (also known as Ebola virus disease) re-emerged on February 2021 in Africa. Ebola’s last stand: Epidemic in West Africa nearing conclusion. This virus is transmitted to people from wild animals and spread in human population through human transmission. Free Ebola Virus Essays and Papers. Ebola virus disease (EVD) is a rare but serious disease caused by infection of the Ebola virus. The 2013–2016 Ebola virus disease outbreak in West Africa mostly affected Guinea, Liberia and Sierra Leone. This can happen when a person touches the infected body fluids or objects that are contaminated with them, such as medical equipment like needles and syringes. Key Challenges to Ebola Surveillance Case Definitions. Several experimental and existing therapies may be options for preventing and treating Ebola virus … †Ebola virus disease associated sequelae and late-onset complications (musculoskeletal disorders, diffuse pain syndrome, chronic fatigue syndrome; neurocognitive disorders, sensory impairments; ocular-visual impairment, secondary cataract), and mental health disorders with the backdrop of … It cannot be over-emphasized that a truly effective international preparedness and response coordination mechanism cannot be managed nationally. Bats are thought to be the natural host to the disease, and initial infection can occur when humans come in contact with a bat or eat an animal that has been infected by a bat. One of these deadly viruses is the Ebola virus, a highly contagious, deadly and mysterious microbe, known to be the most lethal virus known to human kind that have caused many devastation. Clinical Features of Ebola Virus Disease. So far, Ebola has been confined and isolated but there is always a risk of it Then your organs become liquefied. Ebola is a rare and often fatal illness caused by viruses of the family Filoviridae, genus Ebolavirus, which has five viruses: Ebola virus (EBOV), Sudan virus, Bundibugyo virus, Taï Forest virus, and Reston virus.All viruses cause disease in humans except Reston virus, which has caused asymptomatic infections in humans … US Pharm. 25 years later, it resurfaces - and Col. Sam Daniels of the U.S. Army is sent in to investigate it. Sample Paper on Article “why Ebola keeps coming back” by Weller; June 11, 2021. This first outbreak in Conakry was mainly characterized by the young age of predominantly male patients, working in the informal economical sector, or in medical and paramedical occupations. As You scroll down to the Article, Remember, We Can Write Your Assignment and get you an A Grade! Most of the 1,100 human cases, with nearly 800 deaths, developed in Africa due mainly to direct and intimate contact with infected patients. 1. About Ebola. Although the incidence of outbreak is low, the infection is very serious and often fatal. The Ebola Virus Disease case rate is about 50% and they have varied from 25% to 90% in the past outbreaks. The Ebola virus basically causes uncontrollable bleeding externally and internally. Keywords Ebola, Ebola virus, Ebola vaccine, Ebola treatment, antivirals. In Sierra Leone, over 14 000 c ases of Ebola and about 4000 deaths were confirmed between May 2014 and January 2016, which made it the largest documented outbreak of … •The virus is transmitted to people from wild animals and then spreads in the human population through human-to-human transmission. Dalgard, D.W. et al. The mere essence of their existence is not to cause harm, they are living organisms who want to reproduce and spread with the help of a host. Conclusion. Bundibugyo ebolavirus (BDBV): Causes severe hemorrhagic fever in humans, and was endemic in Uganda. Marburg virus is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus.Marburg virus (MARV) causes Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever. 2014;39 (12):33-36. Ebola Virus Disease: Understanding the Current Outbreak. Ebola virus (EBOV) outbreaks have occurred with an increased frequency since 1994 (1, 2).Four species of EBOV are known to cause EBOV disease (EVD) in humans: Zaire (ZEBOV), Sudan (SUBOV), Tai Forest, and Bundibugyo (BDBV) with fatality rates ranging from 25% to 90% ().BDBV is known to have caused only two outbreaks with fatality rates of 32% and 36% (). Out of 116 confirmed cases there were 39 deaths making the death rate 34%. Between humans, the virus spreads only by direct contact with blood or bodily fluids. The problem is Ebola and to get rid of it, we will bring doctors over and we will also have a concert to raise money for research. Marburg virus is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus.Marburg virus (MARV) causes Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever. Was first discovered after an outbreak in Uganda in 2007 and was confirmed as a new species shortly afterwards. 25 years later, it resurfaces - and Col. Sam Daniels of the U.S. Army is sent in to investigate it. Ebola is a virus that is spreading at an excelerating rate. Symptoms of the Ebola Virus include fever, weakness of muscles, muscle pain, headache and sore throat to start out. So Sudan virus has been found in south Sudan in 76, in 79, then in Uganda in 2000, 2012, 2011. A virus similar to Ebola & Lassa is discovered in Africa in 1969. Four of them affect people. Initiative Ebola Crisis – Conclusion and Recommendations. Without doubt, Ebola has put a big impact on the Congo. “Taken together, our results clearly point to the conclusion that [Ebola virus] has gradually spread across central Africa from an origin near Yambuku in the mid-1970s,” they wrote. As of May 19, 2019, there were 1826 confirmed cases and 1218 deaths, making it the second largest outbreak of Ebola virus disease in history, with a case fatality rate of 66%—much higher than previous outbreaks.1 Jeremy Farrar, … Ebola virus is considered as one of the most lethal virus found so far and it has extremely high mortality rate therefore according to the doctors and experts point of view anyone who has stayed in areas where Ebola outbreak have recently been reported should have knowledge about the symptoms of infection and seek medical advices at the first sign of illness. Ebola Virus Disease: an Update on Therapeutics and Vaccines. In conclusion, the Ebola virus currently does not a confirmed resivre it comes from. They changed the name now and the only Ebola virus is formerly known as Zaire Ebola virus. It is the one-year anniversary of Dr. Rick Sacra’s arrival at Nebraska Medicine – Nebraska Medical Center as the first patient to be treated in the Biocontainment Unit for the Ebola virus. Background Ebola Outbreaks and Control Strategies, 1976–2014. This can happen when a person touches the infected body fluids or objects that are contaminated with them, such as medical equipment like needles and syringes. Conclusion: A total of 23 Marburg and Ebola virus outbreaks causing viral hemorrhagic fever has been reported among humans and monkeys since the first outbreak in Marburg, Germany in 1967.
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